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Rheumatoid Arthritis

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What is Rheumatoid Arthritis?

Rheumatoid arthritis (RA) is an autoimmune disease that causes chronic inflammatory arthritis (warm, swollen, painful joints) and may affect other parts of the body including the eyes, lungs, skin, heart, blood vessels and nerves.

Who are at Risk of RA?

RA is more common in women. It usually occurs in people aged between 25 to 50 years old, but young children and elderly may be affected too.

What Causes RA?

The precise cause of RA is unknown. It is likely to be caused by a combination of factors like:

  • Genetics
  • Abnormal immune system
  • Environment (e.g. smoking, stress)
  • Hormones

Symptoms and Signs of RA

In early stages of RA, most people experience:

  • Early morning stiffness
  • Aching of the joints (especially in hands and feet)
  • Fatigue

Overtime, the joints become warm, painful and swollen. The same joints on both sides of the body tend to be affected, especially the hands and feet.

People with RA may also:

  • Lose their appetite
  • Lose weight
  • Develop depression
  • Experience general tiredness and fatigue(dependent on the amount of inflammation the patient has)

Early diagnosis can prevent irreversible joint damage and preserve joint function.

Deformed finger joints (left) and toe joints (right) due to RA. 

How is RA Diagnosed?

RA is diagnosed based on patient's medical history, physical examination and laboratory tests. Imaging may be required if RA is in its early stages or symptoms and signs appear unusual.

The doctor may also drain fluid from your joints to ensure your arthritis is not due to an infection or some other causes.

Your doctor may perform a biopsy to remove small bits of inflamed joint tissue or nodules for examination only when needed.

Common tests performed for RA patients include:

  • Full blood count
  • Kidney function and liver function tests
  • Inflammatory markers tests
  • Auto-antibodies tests
  • X-Rays of affected joints

What are the Treatments for RA?

  1. Patient Education
    This consists of empowering yourself with knowledge and taking charge of your health.
  2. Advice includes:

    • Learn as much as you can about RA.
    • Do not be afraid of arthritis. Most patients with RA lead normal lives.
    • Seek your doctor's advice early
    • Avoid unnecessary strain on affected joints.
    • Take medications as advised by your doctor.
    • Do not change the dosage or types of medication without your doctor's knowledge.
    • Do not rely on unproven remedies in hope that the disease will go away.
    • Do not change doctor unnecessarily because the treatment of RA is complex and long-term. It is best that you build a lasting relationship with your doctor.
    • Get adequate rest and sleep.
    • Join support groups like the National Arthritis Foundation. Scan the QR code below or access https://naf.org.sg/naf-membership-signup/ to join!

     

    National Arthritis Foundation

  3. Medication
    Majority of patients with RA require medications.
    • Non-Steroidal Anti-inflammatory Drugs (NSAIDs)
      Usually used to reduce joint swelling, pain and stiffness.
    • Disease Modifying Anti-rheumatic Drugs (DMARDs)
      Aims to suppress inflammation so that joint pain and swelling are controlled and damage to joints is minimised.
    • Corticosteroids
      Often used in low doses in combination with NSAIDs and DMARDs to enable quick control of inflammation.
  4. Physiotherapy (PT) and Occupational Therapy (OT)
    ‐ Improve pain control using non-pharmacological methods (e.g. heat and cold therapy).
    ‐ Explore ways of improving mobility of injured joints and muscles (e.g. application of splints).
  5. Biologic Agents
    They are medical products extracted or produced from biological sources. They are expensive and reserved for arthritis that is not controlled by standard therapy.
  6. Lifestyle Modification
    Quit smoking, have adequate rest, exercise and maintain ideal body weight

Can a Person With RA Become Pregnant or Have Children?

Yes, a person with RA can become pregnant or have his/her own child. However, as some medications taken may affect pregnancy, please discuss your family plans with your doctor. This also applies to male patients who are planning to start their own family.

What is the Outlook for Patients?

RA can be mild, moderate or severe. Majority of patients improves with treatment in the early stages of RA and lead normal lives. A small percentage of patients may have permanent joint damage and deformities. This may be due to unusually severe disease or negligence.

2022/04/06

 

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2024/09/09
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