The MFF programme is a multi-institutional research programme targeting osteosarcopaenia in the early stages of frailty across the healthcare continuum focussing on high disease burden cohorts such as multimorbidity, stroke, traumatic brain injury, knee osteoarthritis and breast cancer.
It employs multimodal deep phenotyping techniques including socio-demographic data, nutritional markers, physical performance measures, muscle ultrasound, body impedance analysis, bone mineral density, fluid biomarkers and digital biomarkers such as wearables and motion capture AI analytics. It will follow up with participants for 2 to 3 years.
The over-arching mission of the MFF programme is to screen, detect and intervene early in the frailty continuum and shift the curve to the left through data driven approaches to better target personalised pilot interventional trials using multicomponent interventions for healthy aging.
Strong research and innovation collaborations are forged with partner academic institutions such Rehabilitation Research Institute of Singapore (RRIS), NTU, LKC Medicine and relevant industry partners.
SRP Leads
Clinical A/Prof Karen Chua Sui Geok
Senior Consultant
Rehabilitation Medicine
Tan Tock Seng Hospital,
Adjunct Associate Professor
Lee Kong Chian School of Medicine,
Nanyang Technological University
Email
A/Prof Lim Wee Shiong
Senior Consultant
Geriatric Medicine,
Tan Tock Seng Hospital,
Adjunct Associate Professor
Lee Kong Chian School of Medicine,
Nanyang Technological University
Email
A/Prof Lee Eng Sing
Senior Consultant, Family Physician
NHG Polyclinics
Assistant Professor
Lee Kong Chian School of Medicine,
Nanyang Technological University
Email
Partnerships